FB2024_03 , released June 25, 2024
Allele: Ecol\lexAVP16.Clk.4.1M
Open Close
General Information
Symbol
Ecol\lexAVP16.Clk.4.1M
Species
E. coli
Name
FlyBase ID
FBal0296100
Feature type
allele
Associated gene
Ecol\lexA
Associated Insertion(s)
Carried in Construct
P{Clk-lexA.4.1M}
Also Known As
Clk4.1M-LexA, Clk4.1-LexA
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Cavanaugh et al., 2014)
Progenitor genotype
Carried in construct
P{Clk-lexA.4.1M}
Cytology
Description

The 1.6kb Clk 4.1 enhancer fragment regulates expression of a lexA::VP16 driver.

(Cavanaugh et al., 2014)
Allele components
Component
Use(s)
Regulatory region(s)
Clk
Encoded product / tool
lexA::VP16
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      DN1p neuron
      (Cavanaugh et al., 2014)
      DN1 neuron
      (Guo et al., 2016)
      DN1 neuron | subset
      (Sun et al., 2022)
      Additional Information
      Statement
      Reference

      GFP reconstitution across synaptic partners (GRASP) using EcollexAClk.4.1M.T:HsimVP16 shows a connection between ScerGAL4Kurs58 positive PI neurons and EcollexAClk.4.1M.T:HsimVP16 positive DN1p neurons.

      (Cavanaugh et al., 2014)
       
      Marker for
      DN1 neuron
      (Sun et al., 2022, Guo et al., 2016)
      DN1p neuron
      (Cavanaugh et al., 2014)
      Reflects expression of
      Clk
      (Sun et al., 2022, Guo et al., 2016, Cavanaugh et al., 2014)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Ecol\lexAClk.4.1M.T:Hsim\VP16
      Ecol\lexAVP16.Clk.4.1M
      Name Synonyms
      Secondary FlyBase IDs
        References (10)