Ablation of Crz neurons by expressing rprScer\UAS.T:Ivir\HA1.cLa under the control of Scer\GAL4Crz.PC show significantly delayed recovery from ethanol-induced sedation. Recovery from ethyl ether-induced sedation is unaffected.
Expression of rprScer\UAS.T:Ivir\HA1.cLa in the retina under the control of Scer\GAL4GMR.PF results in significant pupal lethality. A few adult escapers are seen that display degenerated eyes.
Expression of rprScer\UAS.T:Ivir\HA1.cLa under the control of Scer\GAL4CCAP.PP results in loss of all CCAP neurons in the third instar larval CNS, and causes severed developmental anomalies and lethality in pupae.