FB2024_03 , released June 25, 2024
Allele: Dmel\knonMI10492
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General Information
Symbol
Dmel\knonMI10492
Species
D. melanogaster
Name
FlyBase ID
FBal0293637
Feature type
allele
Associated gene
Dmel\knon
Associated Insertion(s)
Mi{MIC}knonMI10492
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele

Mutagen
    Nature of the Allele
    Allele class

    hypomorphic allele

    (Sawyer et al., 2017)
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    Mi{MIC}knonMI10492
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    Mi{MIC}
    Also carries
    attP
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        knonMI10492 mutant males display reduced fertility and incompletely penetrant mild mitochondrial elongation defects.

        knonMI10492/Df(2R)7E as well as knonMI10492/knon1400 transheterozygous males are completely sterile and show defective mitochondrial elongation in spermatids.

        (Sawyer et al., 2017)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (3)
        Reported As
        Symbol Synonym
        CG7813MI10492
        (Bellen, 2013.12.12)
        knonMI10492
        knonMi10492
        (Sawyer et al., 2017)
        Name Synonyms
        Secondary FlyBase IDs
          References (2)