UASt regulatory sequences drive expression of a mutant form of Hsap\EWSR1 in which the glycine at amino acid 511 has been replaced by alanine.
Expression of Hsap\EWSR1G511A.Scer\UAS under the control of Scer\GAL4GMR.PF causes degeneration of eye structure.
Expression of Hsap\EWSR1G511A.Scer\UAS throughout the nervous system under the control of Scer\GAL4elav.PLu leads to a shortened lifespan.