FlyBase Allele Report: Dmel\Diap1[UAS.cUa]

General Information

Symbol

Dmel\Diap1^UAS.cUa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Unknown

FlyBase ID

FBal0276787

Feature type

allele

Associated gene

Dmel\Diap1

Associated Insertion(s)

Carried in Construct

P{UAS-Diap1.U}

Also Known As

UAS-DIAP1, UAS-dIAP, UAS DIAP1

Key Links

Transgenic product class

wild_type

(Jones et al., 2012)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Jones et al., 2012)

Mutagen

in vitro construct

(Jones et al., 2012)

Progenitor genotype

Carried in construct

P{UAS-Diap1.U}

Cytology

Description

UAS regulatory sequences drive expression of Diap1.

(Jones et al., 2012)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Diap1

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

DOES NOT model carcinoma

CEA with Egfr^UAS.cBa

(Herranz et al., 2012)

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates myotonic dystrophy type 1

modeled by Zzzz\CTG^i480.UAS.cGa

(Bargiela et al., 2015)

exacerbates myotonic dystrophy type 1

modeled by Zzzz\CTG^i480.UAS.cGa

(Bargiela et al., 2015)

ameliorates cytochrome-c oxidase deficiency disease

modeled by Scox^GD898

(Martínez-Morentin et al., 2015)

ameliorates cancer

modeled by Hsap\CDH3^UASp.cPa

(Faria et al., 2023)

DOES NOT ameliorate cancer

modeled by bi^UAS.cPa

(Shen et al., 2014)

ameliorates carcinoma

modeled by Mef2^UAS.cUa, N^ICN.UAS

(Pallavi et al., 2012)

ameliorates neurodegenerative disease

modeled by mir-bft^Δ263a-G4, mir-bft²⁴

(Aw et al., 2017)

ameliorates severe acute respiratory syndrome

modeled by HCoV-SARS\3a^{UAS.CUHK-W1.EGFP}

(Wong et al., 2005)

ameliorates Machado-Joseph disease

modeled by Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}

(Raj and Sarkar, 2019, Singh et al., 2014)

ameliorates Coronavirus infectious disease

modeled by HCoV-SARS\M^{UAS.CUHK-Su10}

(Chan et al., 2007)

Comments on Models/Modifiers Based on Experimental Evidence ( 1 )

The muscle phenotypes associated with Zzzz\CTG^{i480.Scer\UAS.cGa}, which models human myotonic dystrophy type 1, are ameliorated by Diap1^Scer\UAS.cUa in an inducible system, but in another experiment using a non-inducible driver, the reduced lifespan caused by Zzzz\CTG^{i480.Scer\UAS.cGa} is exacerbated by Diap1^Scer\UAS.cUa.

(Bargiela et al., 2015)

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of Diap1^UAS.cUa under the control of Scer\GAL4^GMR.PS does not lead to any visible changes in the adult eye when compared to controls.

(Tanaka et al., 2019)

The expression of Diap1^UAS.cUa from the second instar larval stage under the combined control of Scer\GAL4^ap-md544 and Gal80[ts] has no significant effect on the size of the third instar larval wing disc dorsal compartment.

(Gerlach et al., 2018)

The expression of Diap1^Scer\UAS.cUa under the control of Scer\GAL4^nos.PU does not lead to a significant proportion of hyperplastic testes, as compared to controls.

(Napoletano et al., 2017)

Expression of Diap1^Scer\UAS.cUa under the control of Scer\GAL4^hs.PU results in a significant decrease in muscle area in dorsoventral sections of the thorax after induction via heat shock, as compared with controls.

(Bargiela et al., 2015)

Expression of Diap1^Scer\UAS.cUa under the control of Scer\GAL4^GMR.PS does not result in any defect in compound eye morphology.

(Huu et al., 2015)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Diap1^UAS.cUa, Scer\GAL4^ap-md544 is an enhancer of abnormal mitotic cell cycle | third instar larval stage phenotype of Scer\GAL4^ap-md544, pnut^GD1512

(Gerlach et al., 2018)

Diap1^UAS.cUa, Scer\GAL4^Mhc.PW is an enhancer of short lived phenotype of Scer\GAL4^Mhc.PW, Zzzz\CTG^i480.UAS.cGa

(Bargiela et al., 2015)

Diap1^UAS.cUa, Scer\GAL4^ap-md544 is an enhancer of abnormal size | third instar larval stage phenotype of Egfr^UAS.cBa, Scer\GAL4^ap-md544

(Herranz et al., 2012)

NOT Enhancer of

Statement

Reference

Diap1^UAS.cUa, Scer\GAL4^ey.PU is a non-enhancer of decreased size | adult stage phenotype of Scer\GAL4^ey.PU, Xpd^KK101234

(Jung et al., 2020)

Diap1^UAS.cUa, Scer\GAL4^hs.2sev is a non-enhancer of increased cell death phenotype of Mmus\Gria1^Lc.UAS, Scer\GAL4^hs.2sev

(Yang et al., 2013)

Suppressor of

Statement

Reference

Diap1^UAS.cUa, Scer\GAL4^ey.PU is a suppressor of decreased size | adult stage phenotype of Ciao1^GD7831, Scer\GAL4^ey.PU

(Jung et al., 2020)

Diap1^UAS.cUa, Scer\GAL4^Bx-MS1096-KE is a suppressor | partially of visible | adult stage phenotype of Lsd-2^GD14108, Scer\GAL4^Bx-MS1096-KE

(Binh et al., 2019)

Diap1^UAS.cUa, Scer\GAL4^Bx-MS1096-KE is a suppressor | partially of increased cell death | third instar larval stage phenotype of Lsd-2^GD14108, Scer\GAL4^Bx-MS1096-KE

(Binh et al., 2019)

Diap1^UAS.cUa is a suppressor of increased cell death | larval stage phenotype of Scer\GAL4^GMR.PS, bocks^HMS01817

(Tanaka et al., 2019)

Diap1^UAS.cUa is a suppressor of visible | adult stage phenotype of Scer\GAL4^GMR.PS, smash^GD10286

(Tanaka et al., 2019)

Diap1^UAS.cUa is a suppressor of increased cell death | larval stage phenotype of Scer\GAL4^GMR.PS, smash^GD10286

(Tanaka et al., 2019)

Diap1^UAS.cUa is a suppressor of increased occurrence of cell division | larval stage phenotype of Scer\GAL4^GMR.PS, smash^GD10286

(Tanaka et al., 2019)

Diap1^UAS.cUa is a suppressor of increased cell death | larval stage phenotype of Ote^GD2067, Scer\GAL4^GMR.PS

(Tanaka et al., 2019)

Diap1^UAS.cUa, Scer\GAL4^ap-md544 is a suppressor of abnormal size | third instar larval stage phenotype of Scer\GAL4^ap-md544, pnut^GD1512

(Gerlach et al., 2018)

Diap1^UAS.cUa, Scer\GAL4^ap-md544 is a suppressor of increased cell death | third instar larval stage phenotype of Scer\GAL4^ap-md544, pnut^GD1512

(Gerlach et al., 2018)

Diap1^UAS.cUa, Scer\GAL4^Bx-MS1096 is a suppressor | partially of atrophy | adult stage phenotype of Lsd-1^GD6641, Scer\GAL4^Bx-MS1096

(Men et al., 2016)

Diap1^UAS.cUa, Scer\GAL4^Bx-MS1096 is a suppressor | partially of visible | adult stage phenotype of Lsd-1^GD6641, Scer\GAL4^Bx-MS1096

(Men et al., 2016)

Diap1^UAS.cUa, Scer\GAL4^GMR.PS is a suppressor of abnormal eye color phenotype of Hsap\BCL2L13^UAS.cNa, Scer\GAL4^GMR.PS

(Nakazawa et al., 2016)

Diap1^UAS.cUa, Scer\GAL4^GMR.PS is a suppressor | partially of visible phenotype of Hsap\BCL2L13^UAS.cNa, Scer\GAL4^GMR.PS

(Nakazawa et al., 2016)

Diap1^UAS.cUa, Scer\GAL4^hs.PU is a suppressor | heat sensitive | partially of abnormal size | adult stage | heat sensitive phenotype of Scer\GAL4^hs.PU, Zzzz\CTG^i480.UAS.cGa

(Bargiela et al., 2015)

Diap1^UAS.cUa, Scer\GAL4^hs.PU is a suppressor | heat sensitive | partially of increased cell death | adult stage | heat sensitive phenotype of Scer\GAL4^hs.PU, Zzzz\CTG^i480.UAS.cGa

(Bargiela et al., 2015)

Diap1^UAS.cUa, Scer\GAL4^salm.EPv is a suppressor of increased cell death phenotype of Scer\GAL4^salm.EPv, caup^UAS.Tag:HA

(Barrios et al., 2015)

Diap1^UAS.cUa, Scer\GAL4^CCAP.PP is a suppressor | partially of visible phenotype of Idh^{R195H.UAS.Tag:FLAG}, Scer\GAL4^CCAP.PP

(Reitman et al., 2015)

Scer\GAL4^NP6701/Diap1^UAS.cUa is a suppressor | partially of short lived phenotype of mir-1000^KO2/mir-1000^KO1

(Verma et al., 2015)

Scer\GAL4^NP6701/Diap1^UAS.cUa is a suppressor of abnormal locomotor behavior | adult stage phenotype of mir-1000^KO2/mir-1000^KO1

(Verma et al., 2015)

Diap1^UAS.cUa, Scer\GAL4^ptc-559.1 is a suppressor of increased cell death | third instar larval stage phenotype of Hsap\APLP1^UAS.cMa, Scer\GAL4^ptc-559.1

(Wang et al., 2015)

Diap1^UAS.cUa, Scer\GAL4^GMR.PF is a suppressor of increased cell death phenotype of Scer\GAL4^GMR.PF, lin-52^GD12885

(Bhaskar et al., 2014)

Diap1^UAS.cUa, Scer\GAL4^GMR.PU is a suppressor of visible phenotype of Scer\GAL4^GMR.PU, Srrm1^GE25979

(Fan et al., 2014)

Diap1^UAS.cUa, Scer\GAL4^sd.PU is a suppressor | partially of increased cell death | larval stage phenotype of Scer\GAL4^sd.PU, p53^UAS.DΔNp53

(Simón et al., 2014)

Diap1^UAS.cUa, Scer\GAL4^sd.PU is a suppressor of increased cell death phenotype of Scer\GAL4^sd.PU, SkpA^HM05185

(Fereres et al., 2013)

Diap1^UAS.cUa, Scer\GAL4^Bx-MS1096-KE is a suppressor | partially of increased cell death phenotype of Scer\GAL4^Bx-MS1096-KE, puf^UAS.WT

(Li et al., 2013)

Diap1^UAS.cUa, Scer\GAL4^en.PU is a suppressor | partially of partially lethal - majority die phenotype of Scer\GAL4^en.PU, parvin^UASp.mGFP6

(Chountala et al., 2012)

Diap1^UAS.cUa, Scer\GAL4^en.PU is a suppressor | partially of increased cell death | larval stage phenotype of Scer\GAL4^en.PU, parvin^UASp.mGFP6

(Chountala et al., 2012)

Ilk^UAS.cZa/Diap1^UAS.cUa, Scer\GAL4^en.PU is a suppressor of partially lethal - majority die phenotype of Scer\GAL4^en.PU, parvin^UASp.mGFP6

(Chountala et al., 2012)

Ilk^UAS.cZa/Diap1^UAS.cUa, Scer\GAL4^en.PU is a suppressor of increased cell death | larval stage phenotype of Scer\GAL4^en.PU, parvin^UASp.mGFP6

(Chountala et al., 2012)

Diap1^UAS.cUa, Scer\GAL4^ap-md544 is a suppressor of increased cell death | third instar larval stage phenotype of Egfr^UAS.cBa, Scer\GAL4^ap-md544

(Herranz et al., 2012)

Diap1^UAS.cUa, Scer\GAL4^GMR.PF is a suppressor of visible phenotype of Asam\aopP^UAS.Tag:MYC, Scer\GAL4^GMR.PF

(Jones et al., 2012, Jones et al., 2008)

NOT Suppressor of

Statement

Reference

Diap1^UAS.cUa, Scer\GAL4^ey.PU is a non-suppressor of decreased size | adult stage phenotype of Scer\GAL4^ey.PU, Xpd^KK101234

(Jung et al., 2020)

Diap1^UAS.cUa, Scer\GAL4^salm.EPv is a non-suppressor of visible phenotype of Scer\GAL4^salm.EPv, caup^UAS.Tag:HA

(Barrios et al., 2015)

Diap1^UAS.cUa, Scer\GAL4^sd.PU is a non-suppressor of neoplasia | larval stage phenotype of Scer\GAL4^sd.PU, p53^UAS.DΔNp53

(Simón et al., 2014)

Diap1^UAS.cUa, Scer\GAL4^hs.2sev is a non-suppressor of increased cell death phenotype of Mmus\Gria1^Lc.UAS, Scer\GAL4^hs.2sev

(Yang et al., 2013)

Diap1^UAS.cUa, Scer\GAL4^Toll-6-D42 is a non-suppressor of short lived phenotype of Hsap\TARDBP^UAS.cHa, Scer\GAL4^Toll-6-D42

(Zhan et al., 2013)

Other

Statement

Reference

Diap1^UAS.cUa, Scer\GAL4^ap-md544, pnut^GD1512, stg^UAS.Tag:HA has abnormal size | third instar larval stage phenotype

(Gerlach et al., 2018)

Phenotype Manifest In

Enhancer of

Statement

Reference

Diap1^UAS.cUa, Scer\GAL4^ap-md544 is an enhancer of wing disc dorsal compartment | third instar larval stage phenotype of Scer\GAL4^ap-md544, pnut^GD1512

(Gerlach et al., 2018)

Diap1^UAS.cUa, Scer\GAL4^ap-md544 is an enhancer of wing disc dorsal compartment | third instar larval stage phenotype of Egfr^UAS.cBa, Scer\GAL4^ap-md544

(Herranz et al., 2012)

NOT Enhancer of

Statement

Reference

Diap1^UAS.cUa, Scer\GAL4^ey.PU is a non-enhancer of eye phenotype of Scer\GAL4^ey.PU, Xpd^KK101234

(Jung et al., 2020)

Diap1^UAS.cUa, Scer\GAL4^hs.2sev is a non-enhancer of eye phenotype of Mmus\Gria1^Lc.UAS, Scer\GAL4^hs.2sev

(Yang et al., 2013)

Suppressor of

Statement

Reference

Diap1^UAS.cUa, Scer\GAL4^ey.PU is a suppressor of eye phenotype of Ciao1^GD7831, Scer\GAL4^ey.PU

(Jung et al., 2020)

Diap1^UAS.cUa, Scer\GAL4^Bx-MS1096-KE is a suppressor | partially of wing phenotype of Lsd-2^GD14108, Scer\GAL4^Bx-MS1096-KE

(Binh et al., 2019)

Diap1^UAS.cUa, Scer\GAL4^Bx-MS1096-KE is a suppressor | partially of wing pouch | third instar larval stage phenotype of Lsd-2^GD14108, Scer\GAL4^Bx-MS1096-KE

(Binh et al., 2019)

Diap1^UAS.cUa, Scer\GAL4^GMR.PS is a suppressor of eye disc phenotype of Scer\GAL4^GMR.PS, bocks^HMS01817

(Tanaka et al., 2019)

Diap1^UAS.cUa, Scer\GAL4^GMR.PS is a suppressor of eye phenotype of Scer\GAL4^GMR.PS, smash^GD10286

(Tanaka et al., 2019)

Diap1^UAS.cUa, Scer\GAL4^GMR.PS is a suppressor of eye disc phenotype of Scer\GAL4^GMR.PS, smash^GD10286

(Tanaka et al., 2019)

Diap1^UAS.cUa, Scer\GAL4^GMR.PS is a suppressor of eye disc phenotype of Ote^GD2067, Scer\GAL4^GMR.PS

(Tanaka et al., 2019)

Diap1^UAS.cUa, Scer\GAL4^ap-md544 is a suppressor of wing disc dorsal compartment | third instar larval stage phenotype of Scer\GAL4^ap-md544, pnut^GD1512

(Gerlach et al., 2018)

Diap1^UAS.cUa, Scer\GAL4^Bx-MS1096 is a suppressor | partially of wing phenotype of Lsd-1^GD6641, Scer\GAL4^Bx-MS1096

(Men et al., 2016)

Diap1^UAS.cUa, Scer\GAL4^GMR.PS is a suppressor | partially of eye phenotype of Hsap\BCL2L13^UAS.cNa, Scer\GAL4^GMR.PS

(Nakazawa et al., 2016)

Diap1^UAS.cUa, Scer\GAL4^GMR.PS is a suppressor | partially of interommatidial bristle phenotype of Hsap\BCL2L13^UAS.cNa, Scer\GAL4^GMR.PS

(Nakazawa et al., 2016)

Diap1^UAS.cUa, Scer\GAL4^GMR.PS is a suppressor | partially of ommatidium phenotype of Hsap\BCL2L13^UAS.cNa, Scer\GAL4^GMR.PS

(Nakazawa et al., 2016)

Diap1^UAS.cUa, Scer\GAL4^hs.PU is a suppressor | heat sensitive | partially of adult somatic muscle cell of thorax | heat sensitive phenotype of Scer\GAL4^hs.PU, Zzzz\CTG^i480.UAS.cGa

(Bargiela et al., 2015)

Diap1^UAS.cUa, Scer\GAL4^salm.EPv is a suppressor | partially of wing disc phenotype of Scer\GAL4^salm.EPv, caup^UAS.Tag:HA

(Barrios et al., 2015)

Diap1^UAS.cUa, Scer\GAL4^tin.CΔ4 is a suppressor of adult heart phenotype of Scer\GAL4^tin.CΔ4, Scox^GD898

(Martínez-Morentin et al., 2015)

Diap1^UAS.cUa, Scer\GAL4^tin.CΔ4 is a suppressor of cardiac myofibril | adult stage phenotype of Scer\GAL4^tin.CΔ4, Scox^GD898

(Martínez-Morentin et al., 2015)

Diap1^UAS.cUa, Scer\GAL4^CCAP.PP is a suppressor | partially of wing phenotype of Idh^{R195H.UAS.Tag:FLAG}, Scer\GAL4^CCAP.PP

(Reitman et al., 2015)

Diap1^UAS.cUa, Scer\GAL4^ptc-559.1 is a suppressor of anterior-posterior compartment boundary of the wing disc | third instar larval stage phenotype of Hsap\APLP1^UAS.cMa, Scer\GAL4^ptc-559.1

(Wang et al., 2015)

Diap1^UAS.cUa, Scer\GAL4^GMR.PF is a suppressor of eye phenotype of Scer\GAL4^GMR.PF, lin-52^GD12885

(Bhaskar et al., 2014)

Diap1^UAS.cUa, Scer\GAL4^GMR.PF is a suppressor of ommatidium phenotype of Scer\GAL4^GMR.PF, lin-52^GD12885

(Bhaskar et al., 2014)

Diap1^UAS.cUa, Scer\GAL4^GMR.PF is a suppressor of interommatidial bristle phenotype of Scer\GAL4^GMR.PF, lin-52^GD12885

(Bhaskar et al., 2014)

Diap1^UAS.cUa, Scer\GAL4^GMR.PU is a suppressor of eye phenotype of Scer\GAL4^GMR.PU, Srrm1^GE25979

(Fan et al., 2014)

Diap1^UAS.cUa, Scer\GAL4^sd.PU is a suppressor | partially of wing pouch phenotype of Scer\GAL4^sd.PU, p53^UAS.DΔNp53

(Simón et al., 2014)

Diap1^UAS.cUa, Scer\GAL4^sd.PU is a suppressor of wing disc phenotype of Scer\GAL4^sd.PU, SkpA^HM05185

(Fereres et al., 2013)

Diap1^UAS.cUa, Scer\GAL4^en.PU is a suppressor | partially of wing phenotype of RYBP^RNAi.UAS.cGa, Scer\GAL4^en.PU

(Fereres et al., 2013)

Diap1^UAS.cUa, Scer\GAL4^en.PU is a suppressor | partially of wing disc posterior compartment phenotype of Scer\GAL4^en.PU, parvin^UASp.mGFP6

(Chountala et al., 2012)

Ilk^UAS.cZa/Diap1^UAS.cUa, Scer\GAL4^en.PU is a suppressor of wing disc posterior compartment phenotype of Scer\GAL4^en.PU, parvin^UASp.mGFP6

(Chountala et al., 2012)

Diap1^UAS.cUa, Scer\GAL4^en.PU is a suppressor | partially of filamentous actin phenotype of Scer\GAL4^en.PU, parvin^UASp.mGFP6

(Chountala et al., 2012)

Diap1^UAS.cUa, Scer\GAL4^ap-md544 is a suppressor of wing disc dorsal compartment | third instar larval stage phenotype of Egfr^UAS.cBa, Scer\GAL4^ap-md544

(Herranz et al., 2012)

Diap1^UAS.cUa, Scer\GAL4^GMR.PF is a suppressor of eye phenotype of Asam\aopP^UAS.Tag:MYC, Scer\GAL4^GMR.PF

(Jones et al., 2012, Jones et al., 2008)

NOT Suppressor of

Statement

Reference

Diap1^UAS.cUa, Scer\GAL4^ey.PU is a non-suppressor of eye phenotype of Scer\GAL4^ey.PU, Xpd^KK101234

(Jung et al., 2020)

Diap1^UAS.cUa, Scer\GAL4^salm.EPv is a non-suppressor of wing phenotype of Scer\GAL4^salm.EPv, caup^UAS.Tag:HA

(Barrios et al., 2015)

Diap1^UAS.cUa, Scer\GAL4^salm.EPv is a non-suppressor of wing vein phenotype of Scer\GAL4^salm.EPv, caup^UAS.Tag:HA

(Barrios et al., 2015)

Diap1^UAS.cUa, Scer\GAL4^C-765 is a non-suppressor of wing disc | third instar larval stage phenotype of Scer\GAL4^C-765, bi^UAS.cPa

(Shen et al., 2014)

Diap1^UAS.cUa, Scer\GAL4^C-765 is a non-suppressor of epithelial cell | third instar larval stage phenotype of Scer\GAL4^C-765, bi^UAS.cPa

(Shen et al., 2014)

Diap1^UAS.cUa, Scer\GAL4^C-765 is a non-suppressor of extracellular matrix | third instar larval stage phenotype of Scer\GAL4^C-765, bi^UAS.cPa

(Shen et al., 2014)

Diap1^UAS.cUa, Scer\GAL4^hs.2sev is a non-suppressor of eye phenotype of Mmus\Gria1^Lc.UAS, Scer\GAL4^hs.2sev

(Yang et al., 2013)

Scer\GAL4^en.PU, Ilk^UAS.cZa, Diap1^UAS.cUa is a non-suppressor of posterior crossvein phenotype of Scer\GAL4^69B, parvin^UASp.mGFP6

(Chountala et al., 2012)

Other

Statement

Reference

Diap1^UAS.cUa, Scer\GAL4^ap-md544, pnut^GD1512, stg^UAS.Tag:HA has wing disc dorsal compartment | third instar larval stage phenotype

(Gerlach et al., 2018)

Additional Comments

Genetic Interactions

Statement

Reference

The co-expression of Diap1^UAS.cUa suppresses the smaller size and the apoptosis, while enhancing the polyploidy/aneuploidy, observed in the third instar larval wing disc dorsal compartment upon the expression of pnut^GD1512 from the second instar larval stage under the combined control of Scer\GAL4^ap-md544 and Gal80[ts].

The triple co-expression of Diap1^UAS.cUa, stg^UAS.Tag:HA and pnut^GD1512 from the second instar larval stage under the combined control of Scer\GAL4^ap-md544 and Gal80[ts] leads to the significant enlargement of the third instar larval wing disc dorsal compartment, as compared to the Diap1^UAS.cUa, pnut^GD1512 double expression condition.

(Gerlach et al., 2018)

Co-expression of Diap1^Scer\UAS.cUa partially rescues the wing atrophy phenotype of flies expressing Lsd-1^GD6641 under the control of Scer\GAL4^Bx-MS1096.

(Men et al., 2016)

Expression of Diap1^Scer\UAS.cUa suppresses the apoptosis seen in the wing disc when caup^{Scer\UAS.T:Ivir\HA1} is expressed under the control of Scer\GAL4^salm.EPv. The wing size, vein pattern and wing notching phenotypes are not modified by Diap1^Scer\UAS.cUa.

(Barrios et al., 2015)

Co-expression of Diap1^Scer\UAS.cUa rescues the rough eye phenotype of adults, and the eye disc apoptosis and proliferation phenotype of larvae expressing OSCP1^Scer\UAS.cHa under the control of Scer\GAL4^GMR.PS.

(Huu et al., 2015)

Co-expression of Diap1^Scer\UAS.cUa rescues heart structural defects seen in Scer\GAL4^tin.CΔ4>Scox^GD898 flies.

(Martínez-Morentin et al., 2015)

Expression of Diap1^Scer\UAS.cUa under the control of Scer\GAL4^mGluR-NP6701 partially suppresses the short lived phenotype of mir-1000^KO1/mir-1000^KO2 adults and reduces the number of Caspase-3 positive cells seen in the adult brain of these flies. The climbing defects are also rescued.

(Verma et al., 2015)

Overexpression of Diap1^Scer\UAS.cUa in the eye-antennal disc expressing lin-52^GD12885, with both transgenes under the control of Scer\GAL4^GMR.PF, suppresses the increase in apoptosis seen upon downregulation of lin-52 alone.

(Bhaskar et al., 2014)

Expression of Diap1^Scer\UAS.cUa suppresses the eye roughness seen when SRm160^GE25979 is expressed under the control of Scer\GAL4^GMR.PU.

(Fan et al., 2014)

The co-expression of Diap1^Scer\UAS.cUa does not suppress the basal delamination of cells observed upon the expression of bi^Scer\UAS.cBa under the control of Scer\GAL4^C-765 in third instar larval wing discs.

(Shen et al., 2014)

Additional expression of Diap1^UAS.cUa in individuals expressing p53^UAS.DΔNp53 under the control of Scer\GAL4^sd.PU reduces cell death (activated caspase 3 staining), but does not prevent overgrowths in the wing pouch; these Diap1^UAS.cUa and p53^UAS.DΔNp53 co-expressing wing discs become smaller upon additional expression of N^TRiP.cUa.

(Simón et al., 2014)

Co-expression of Diap1^Scer\UAS.cUa strongly reduces the cell death induced in wing discs by Scer\GAL4^sd.PU-mediated expression of SkpA^HM05185.

Co-expression of Diap1^Scer\UAS.cUa reduces the penetrance of wing blisters in RYBP^{dsRNA.Scer\UAS.cGa} Scer\GAL4^en.PU flies.

(Fereres et al., 2013)

Xenogenetic Interactions

Statement

Reference

Co-expression of Diap1^Scer\UAS.cUa suppresses the reduction of eye pigments and weakly suppresses the abnormal formation of ommatidia and bristles and reduced eye size seen in Scer\GAL4^GMR.PS>Hsap\BCL2L13^Scer\UAS.cNa flies. Co-expression of Diap1^Scer\UAS.cUa in Scer\GAL4^GMR.PS>Hsap\BCL2L13^{ΔTM.Scer\UAS} flies does not result in eye phenotypes.

(Nakazawa et al., 2016)

Co-expression of Diap1^Scer\UAS.cUa partially suppresses the decreased muscle area and increased autophagy and apoptosis seen in flies expressing Zzzz\CTG^{i480.Scer\UAS.cGa} under the control of Scer\GAL4^hs.PU in response to heat shock; but enhances the shortened lifespan of flies expressing Zzzz\CTG^{i480.Scer\UAS.cGa} under the control of Scer\GAL4^Mhc.PW.

(Bargiela et al., 2015)

Co-expression of Diap1^Scer\UAS.cUa suppresses the increased cell death induced by expression of Hsap\APLP1^Scer\UAS.cMa driven along the anterior/posterior compartment boundary in third instar larval wing discs by Scer\GAL4^ptc-559.1.

(Wang et al., 2015)

Inhibition of apoptosis, through co-expression of th^Scer\UAS.cUa, does not affect the Mmus\Gria1^Lc.Scer\UAS eye defect (when all are expressed under the control of Scer\GAL4^hs.2sev.

(Yang et al., 2013)

Co-expression of th^Scer\UAS.cUa using Scer\GAL4^GMR.PF markedly suppresses the eye phenotype caused by the expression of Zzzz\aopP^{Scer\UAS.T:Hsap\MYC}.

(Jones et al., 2012)

Expression of th^Scer\UAS.cUa suppresses the rough eye phenotype seen when Zzzz\aopP^{Scer\UAS.T:Hsap\MYC} is expressed under the control of Scer\GAL4^GMR.PF.

(Jones et al., 2008)

Complementation and Rescue Data

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Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Diap1^Scer\UAS.cUa

Diap1^UAS.cUa

th^Scer\UAS.cUa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Unknown

Secondary FlyBase IDs

References (65)

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