FB2024_03 , released June 25, 2024
Allele: Dmel\LhrTag:HA
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General Information
Symbol
Dmel\LhrTag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0268225
Feature type
allele
Associated gene
Dmel\Lhr
Associated Insertion(s)
Carried in Construct
M{mel-Lhr-HA}
P{mel-Lhr-HA}
P{ΔBap55.mel-Lhr-HA}
Also Known As
mel-Lhr-HA
Key Links
Transgenic product class
genomic_DNA
(Maheshwari and Barbash, 2012)
wild_type
(Maheshwari and Barbash, 2012)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Maheshwari and Barbash, 2012)
wild_type
(Maheshwari and Barbash, 2012)
Mutagen
in vitro construct
(Maheshwari and Barbash, 2012)
Progenitor genotype
Lhr+t4.8
(Maheshwari and Barbash, 2012)
Carried in construct
M{mel-Lhr-HA}
P{mel-Lhr-HA}
P{ΔBap55.mel-Lhr-HA}
Cytology
Description

Three copies of the Tag:HA tag have been inserted at the C-terminal end of the Lhr coding region.

(Maheshwari and Barbash, 2012)
Allele components
Component
Use(s)
Regulatory region(s)
Lhr
Encoded product / tool
Lhr
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Hybrid Hmr1 males (progeny of Hmr1 LhrT:Ivir\HA1 D. melanogaster females mated to D. mauritiana males) carrying LhrT:Ivir\HA1 show 32-44% viability at room temperature and 52-69% viability at 18[o]C (compared to hybrid Hmr1 males not carrying LhrT:Ivir\HA1).

      (Maheshwari and Barbash, 2012)

      LhrT:Ivir\HA1 fully complements Dsim\Lhr1, which is observed as hybrid male inviability in the progeny of a cross of D. melanogaster females carrying LhrT:Ivir\HA1 to D. simulans Dsim\Lhr1 males.

      LhrT:Ivir\HA1 has little effect on the viability of hybrid HmrDf males (progeny of HmrDf LhrT:Ivir\HA1 D. melanogaster females mated to either D. simulans or D. mauritiana males).

      LhrT:Ivir\HA1 reduces the viability of hybrid Hmr1 males (progeny of Hmr1 LhrT:Ivir\HA1 D. melanogaster females mated to either D. simulans or D. mauritiana males).

      (Maheshwari and Barbash, 2012)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      LhrT:Ivir\HA1
      LhrTag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (3)