UAS regulatory sequences drive expression of an inverted repeat.
The adulthood-only expression of saxJF03431 under the control of Scer\GAL4esg.PU (in combination with Gal80[ts], for temporal regulation of expression) leads to a significant decrease in the relative and absolute size of secondary cell nuclei compared to neighboring main cells and wild-type controls; this expression does not affect the size of main cell nuclei compared to controls. The adulthood-only expression under the control of Scer\GAL4dsx.KI (and Gal80[ts]) leads to a significant increase in the number of secretory vesicles within accessory gland secondary cells, but does not significantly affect the size of the largest multivesicular body/lysosome, as compared to controls; there is also a severe decrease in the secretion of (CD63-positive) exosomes into the accessory gland lumen.
The adulthood-only expression of saxJF03431 under the combined control of Scer\GAL4spi-NP0261 and Gal80[ts] also results in both virgin and mated males showing a significant increase in the number of dense core granule compartments within accessory gland secondary cells, as compared to matched controls.
saxJF03431/Scer\GAL4elav.PU is a non-enhancer of abnormal neuroanatomy | larval stage phenotype of Scer\GAL4elav.PU, Sec15KK101708
saxJF03431/Scer\GAL4elav.PU is a non-suppressor of abnormal neuroanatomy | larval stage phenotype of Scer\GAL4elav.PU, Sec15KK101708
saxJF03431/Scer\GAL4elav.PU is a non-enhancer of NMJ bouton | larval stage | increased number phenotype of Scer\GAL4elav.PU, Sec15KK101708
saxJF03431/Scer\GAL4elav.PU is a non-enhancer of embryonic/larval neuromuscular junction | larval stage phenotype of Scer\GAL4elav.PU, Sec15KK101708
saxJF03431/Scer\GAL4elav.PU is a non-suppressor of NMJ bouton | increased number | larval stage phenotype of Scer\GAL4elav.PU, Sec15KK101708
saxJF03431/Scer\GAL4elav.PU is a non-suppressor of embryonic/larval neuromuscular junction | larval stage phenotype of Scer\GAL4elav.PU, Sec15KK101708