The indirect flight muscles of pupae carrying MhcEMB-11d in a Mhc10 background assemble myofibrils properly and have normal hexagonal packing of thick and thin filaments. Sarcomeres have well-formed M- and Z-lines. 1 week old adults show degeneration of the indirect flight muscle myofibrils with disruption of the hexagonal packing of thick and thin filaments. Sarcomeres appear hypercontracted with disrupted M-lines.
MhcEMB-11d does not rescue flight or jump ability in a Mhc10 background.