FB2024_03 , released June 25, 2024
Allele: Dmel\Trim915
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General Information
Symbol
Dmel\Trim915
Species
D. melanogaster
Name
FlyBase ID
FBal0266854
Feature type
allele
Associated gene
Dmel\Trim9
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Morikawa et al., 2011)
Progenitor genotype
P{GawB}Trim9NP4638
(Morikawa et al., 2011)
Cytology
Description

Imprecise excision of the P{GawB} element in P{GawB}Trim9NP4638 resulted in a 1.7kb deletion 8bp downstream of the insertion site. A 540 base insertion remains in the deleted region.

(Morikawa et al., 2011)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2L:10,545,260..10,546,960 [+]
Comment:

1.7 kb deletion resulting from the imprecise excision of P{GawB}Trim9NP4638, starts 8bp from insertion site and extends into Trim9 gene. Downstream breakpoint approximate.

(Morikawa et al., 2011)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous Trim915 third instar larvae show a marked loss of C4da commissural fascicles in the ventral nerve cord. Axonal defects are visible by embryonic stage 17.

      Trim915/Df(2L)Exel8026 third instar larvae show a marked loss of C4da commissural fascicles in the ventral nerve cord. Axonal defects are visible by embryonic stage 17.

      (Morikawa et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Trim915
      asap15
      (Morikawa et al., 2011)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)