FB2024_03 , released June 25, 2024
Allele: Dmel\magUAS.cSa
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General Information
Symbol
Dmel\magUAS.cSa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Sieber
FlyBase ID
FBal0260740
Feature type
allele
Associated gene
Dmel\mag
Associated Insertion(s)
Carried in Construct
P{UAS-mag.S}
Also Known As
UAS-magro
Key Links
Transgenic product class
cDNA
(Sieber and Thummel, 2009)
wild_type
(Sieber and Thummel, 2009)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Sieber and Thummel, 2009)
wild_type
(Sieber and Thummel, 2009)
Mutagen
in vitro construct
(Sieber and Thummel, 2009)
Progenitor genotype
Carried in construct
P{UAS-mag.S}
Cytology
Description

UASt drives expression of the LP10120 mag cDNA.

(Sieber and Thummel, 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
mag
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Scer\GAL4mex1.2.1-mediated expression of magScer\UAS.cSa in Hr961 mutants is sufficient to reduce the elevated cholesterol levels in these animals.

      Scer\GAL4bab1-Agal4-5-mediated expression of magScer\UAS.cSa in Hr961 mutants is sufficient to rescue the reduced triacylglycerol levels, but not the elevated cholesterol levels, in these animals.

      (Sieber and Thummel, 2012)

      Expression of magScer\UAS.cSa in the midgut using Scer\GAL4mex1.2.1 rescues the lean phenotype (reduced levels of whole-animal triacylglycerol) of Hr961 mutants.

      (Sieber and Thummel, 2009)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      CG5932Scer\UAS.cSa
      magScer\UAS.cSa
      magUAS.cSa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Sieber
      Secondary FlyBase IDs
        References (3)