A 3681 base pair fragment from the flanking non-coding or intronic region of 5-HT2 is fused upstream of a Drosophila core synthetic promoter (DSCP) that is followed by sequence encoding a GAL4 driver.
Optogenetic activation (using Crei\ChR2UAS.cSa with 470 nm (blue) light) of Scer\GAL4GMR49E12 cells in larvae results in a significant increase in turn-avoid behaviors, compared to controls.