UAS regulatory sequences drive expression of an inverted repeat.
Expressing Tango14JF01144 under the control of Scer\GAL4elav.PU impairs climbing in adult flies. Expressing Tango14JF01144 under the control of Scer\GAL4ple.PU results in significantly reduced numbers of dopaminergic PPL1 neurons in 3 and 30 day old flies, and a reduced number of dopaminergic PPM1/2 neurons in 30 day old, but not 3 day old flies. There is no change in the number of dopaminergic PPM3 neurons. 30 day-old flies expressing Tango14JF01144 under the control of Scer\GAL4elav.PU contain apoptotic cells in the brain.