FB2024_03 , released June 25, 2024
Allele: Dmel\raptorJF01087
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General Information
Symbol
Dmel\raptorJF01087
Species
D. melanogaster
Name
FlyBase ID
FBal0245406
Feature type
allele
Associated gene
Dmel\raptor
Associated Insertion(s)
Carried in Construct
P{TRiP.JF01087}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Ni et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Ni et al., 2008)
Mutagen
in vitro construct
(Ni et al., 2008)
Progenitor genotype
Carried in construct
P{TRiP.JF01087}
Cytology
Description

UAS regulatory sequences drive expression of an inverted repeat.

(Ni et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dsRNA-JF01087
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression under the control of Scer\GAL4eya.enh1+E+2 results in a small eye phenotype.

      (Pletcher et al., 2019)

      Expression of raptorJF01087 in cardiac muscle under the control of Scer\GAL4GMR88D05 has no effect on pupal eclosion rates.

      Expression of raptorJF01087 in skeletal muscle under the control of Scer\GAL4how-24B results in lethality.

      Expression of raptorJF01087 under the control of Scer\GAL4c179 causes partial lethality. The number of pupae formed does not differ from controls. A large number of the flies that do eclose die shortly afterwards, but the flies that survive generally have a normal lifespan. Many flies have a reduced climbing rate compared with controls.

      Expression of raptorJF01087 under the control of Scer\GAL4Mef2.PR is lethal. The number of pupae formed does not differ from controls. If the flies are manually removed from the pupal cases they survive with climbing defects.

      Expression of raptorJF01087 under the control of Scer\GAL4Mhc.F3-580 has no effect on pupal eclosion rates and the adult flies do not exhibit any significant climbing defects. Lifespan is reduced compared with controls.

      (Hatfield et al., 2015)

      Scer\GAL4Ilp2.PR-mediated expression results in a significant reduction in the body weight of emerging adults compared to controls.

      (Hasygar and Hietakangas, 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Raptor[JF01087]
      (Nagy et al., 2015)
      raptorJF01087
      Name Synonyms
      Secondary FlyBase IDs
        References (9)