FB2024_03 , released June 25, 2024
Allele: Dmel\Z2-2626Z2-2626
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General Information
Symbol
Dmel\Z2-2626Z2-2626
Species
D. melanogaster
Name
FlyBase ID
FBal0243425
Feature type
allele
Associated gene
Z2-2626
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Wu et al., 2008)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutant males and females show a significant reduction in both nighttime and daytime daily sleep compared to controls. Waking activity (activity/minutes awake) is slightly reduced in the mutant flies compared to controls. There is a significant reduction in sleep bout duration during the night in the mutant flies compared to controls, indicating a defect in sleep maintenance. Sleep bout number in mutant and control flies is not significantly different. Mutant flies show significantly increased sleep rebound after mechanical sleep deprivation compared to control flies. The mutant flies have reduced arousal thresholds from sleep compared to controls.

      (Wu et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Z2-2626
      (Wu et al., 2008)
      Z2-2626Z2-2626
      Name Synonyms
      Secondary FlyBase IDs
        References (1)