Deletion of 88bp of genomic sequence, including 83bp of the 3'UTR of kcc. Generated by imprecise excision of the P{SUPor-P}SERCAKG02390 insertion.
kccML1 homozygotes have a low penetrance (9%) bang sensitive phenotype (i.e.- they exhibit temporary paralysis in response to 10 seconds of vortexing). The same phenotype is seen in kccDHS1/kccML1 or kccAd-4/kccML1 animals, and at a higher penetrance (41%) in kccEY08304/kccML1 or kccDHS1/kccP20-180 animals.
kcc transcript levels are significantly reduced in animals homozygous for kccML1.