UAS regulatory sequences drive expression of an inverted repeat.
The adulthood-only expression of putJF02664 under the control of Scer\GAL4esg.PU (in combination with Gal80[ts], for temporal regulation of expression) leads to a significant decrease in the relative and absolute size of secondary cell nuclei compared to neighboring main cells and wild-type controls; this expression does not affect the size of main cell nuclei compared to controls. The adulthood-only expression under the control of Scer\GAL4dsx.KI (and Gal80[ts]) leads to a significant decrease in the number of secretory vesicles within accessory gland secondary cells, but does not significantly affect the size of the largest multivesicular body/lysosome, as compared to controls; there is also a severe decrease in the secretion of (CD63-positive) exosomes into the accessory gland lumen.
Expression of putJF02664 in muscle under the control of Scer\GAL4Mef2.PU results in significant hyperglycaemia.
Expression of putJF02664 in the fat body under the control of Scer\GAL4DcG results in significant hyperglycaemia.