FB2024_03 , released June 25, 2024
Allele: Ecol\lacZPvf2.PC
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General Information
Symbol
Ecol\lacZPvf2.PC
Species
E. coli
Name
PDGF- and VEGF-related factor 2 promoter construct of Choi
FlyBase ID
FBal0241841
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
Carried in Construct
P{Pvf2-lacZ.C}
Also Known As
pvf2-lacZ
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Choi et al., 2008)
Progenitor genotype
Carried in construct
P{Pvf2-lacZ.C}
Cytology
Description

A 1501bp fragment from -1220 to +281bp relative to the transcription start site of Pvf2 is fused upstream of a lacZ reporter.

(Choi et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
Pvf2_-1220/+281
Encoded product / tool
lacZ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage
      embryonic/larval foregut

      Comment: early stages

      (Choi et al., 2008)
      embryonic/larval hindgut

      Comment: early stages

      (Choi et al., 2008)
      embryonic stage 14
      embryonic/larval gut

      Comment: whole gut

      (Choi et al., 2008)
      third instar larval stage
      embryonic/larval gut

      Comment: whole gut

      (Choi et al., 2008)
      adult stage
      intestinal stem cell
      (Choi et al., 2008)
      enteroblast
      (Choi et al., 2008)
      intestinal stem cell of posterior adult midgut epithelium
      (Bond and Foley, 2012)
      Additional Information
      Statement
      Reference

      transcript is expresed in intestinal stem cells in the adult posterior midgut. Expression colocalizes with that of Pvr protein and Dl reporters. Expression is not observed in enteroblasts.

      (Bond and Foley, 2012)
       
      Marker for
      Reflects expression of
      Pvf2
      (Bond and Foley, 2012, Choi et al., 2008)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Ecol\lacZPvf2.PC
      Name Synonyms
      PDGF- and VEGF-related factor 2 promoter construct of Choi
      Secondary FlyBase IDs
        References (5)