FB2024_03 , released June 25, 2024
Allele: Dmel\psdMF56
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General Information
Symbol
Dmel\psdMF56
Species
D. melanogaster
Name
FlyBase ID
FBal0240495
Feature type
allele
Associated gene
Dmel\psd
Associated Insertion(s)
TI{TI}psdMF56
Carried in Construct
Key Links
Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Elalayli et al., 2008)
Mutagen
recombination
(Elalayli et al., 2008)
FLPase
(Elalayli et al., 2008)
I-SceI
(Elalayli et al., 2008)
ends-out gene targeting
(Elalayli et al., 2008)
Progenitor genotype
P{FRT(psd.KO.Scer\SceI.RS)}
(Elalayli et al., 2008)
Associated Insertion(s)
TI{TI}psdMF56
Cytology
Description

The psd gene has been deleted and replaced by a w+mW.hs marker.

(Elalayli et al., 2008)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In

      microvillus & follicle cell

      (Elalayli et al., 2008)
      Detailed Description
      Statement
      Reference

      20-30% of eggs laid by homozygous females are collapsed at or soon after oviposition, and the remainder are very fragile to handling, but do not usually collapse unless in a dry environment.

      Stage 10A mutant egg chambers show a "boulders and gaps" appearance of the vitelline bodies. During coalescence of the vitelline membrane during stage 10B, there appears to be trapping of microvilli within the vitelline membrane. The final vitelline membrane does not contain gaps, and the architecture of the chorion layers is normal.

      The follicle cells of stage 10A homozygous egg chambers show grossly disorganised microvilli. There is a widening of the perivitelline space between the oocyte and the follicle cell epithelium compared to in wild type.

      (Elalayli et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      psdMF56
      (Elalayli et al., 2008)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)