UASt regulatory sequences drive expression of an inverted repeat.
Flies expressing simjKK107461 under the control of Scer\GAL4elav.PU (in the presence of Dcr-2Scer\UAS.cDa to enhance RNAi efficiency) show impaired habituation: they habituate slower than wild-type controls and maintain a higher jump response throughout the entire course of the experiment.
Expression of simjKK107461 under the control of Scer\GAL4elav.PU (in the presence of Dcr-2Scer\UAS.cDa) results in a neuromuscular junction (NMJ) under-growth phenotype in third instar larvae. There is a significant decrease in synaptic area, perimeter and length. The number of synaptic branches and branching points is also significantly reduced and there is a significant decrease in the number of active zones at the NMJ.