FB2024_03 , released June 25, 2024
Allele: Dmel\Npc2bUAS.cHa
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General Information
Symbol
Dmel\Npc2bUAS.cHa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Huang
FlyBase ID
FBal0221255
Feature type
allele
Associated gene
Dmel\Npc2b
Associated Insertion(s)
Carried in Construct
P{UAS-Npc2b.H}
Key Links
Transgenic product class
cDNA
(Huang et al., 2007)
wild_type
(Huang et al., 2007)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Huang et al., 2007)
wild_type
(Huang et al., 2007)
Mutagen
in vitro construct
(Huang et al., 2007)
Progenitor genotype
Carried in construct
P{UAS-Npc2b.H}
Cytology
Description

UASt regulatory sequences drive expression of the full length Npc2b cDNA.

(Huang et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Npc2b
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of Npc2bScer\UAS.cHa under the control of Scer\GAL4tub or Scer\GAL42-286 rescues the lethality seen in Npc2aunspecified ; Npc2bunspecified double homozygotes, such that 83% or 86% respectively of the double mutants survive to adulthood.

      (Huang et al., 2007)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Npc2bScer\UAS.cHa
      Npc2bUAS.cHa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Huang
      Secondary FlyBase IDs
        References (1)