FB2024_03 , released June 25, 2024
Allele: Dmel\Syx17JF01937
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General Information
Symbol
Dmel\Syx17JF01937
Species
D. melanogaster
Name
FlyBase ID
FBal0219923
Feature type
allele
Associated gene
Dmel\Syx17
Associated Insertion(s)
Carried in Construct
P{TRiP.JF01937}
Also Known As
Syx17 RNAi, UAS-Syx17RNAI, JF01937, UAS-Syx17 RNAi, syx17-RNAi, UAS-Syx17-RNAi, Stx17 RNAi
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Perkins et al., 2009.1.15)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Perkins et al., 2009.1.15)
Mutagen
in vitro construct
(Perkins et al., 2009.1.15)
Progenitor genotype
Carried in construct
P{TRiP.JF01937}
Cytology
Description

UAS regulatory sequences drive expression of an inverted repeat.

(Perkins et al., 2009.1.15)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dsRNA-JF01937
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Adulthood-only expression of Syx17JF01937 under the control of Scer\GAL4esg.PU leads to a significant increase in the number of mitotic cells (phospho-H3 staining) in the adult midgut, as compared to controls. (The temporal regulation of expression is dependent on Gal80[ts] and induced by temperature shift to 29[o]C for 5-6 days during adulthood).

      (Zhang et al., 2019)

      The expression of Syx17JF01937 under the control of Scer\GAL4Cg.PA results in early third instar larval fat bodies with moderate accumulation of small autophagosomes and lysosomes, as compared to controls.

      (Liu et al., 2018)

      Scer\GAL4He.PZ-driven expression of Syx17JF01937 does not induce increase in the number of circulating hemocytes in third instar larvae relative to controls.

      (Del Signore et al., 2017)

      Expression of Syx17JF01937 under the control of Scer\GAL4ple.PU (in combination with a Dicer-2 transgene to enhance RNAi efficiency) causes significantly decreased numbers of PPL1 dopaminergic neurons after 48h at 29[o]C, as compared with controls.

      (Babcock et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Suppressed by
      NOT suppressed by
      Statement
      Reference

      Scer\GAL4NP0001, Syx17JF01937 has adult gut phenotype, non-suppressible by EgfrDN.UAS.cBa, Scer\GAL4NP0001

      (Nassari et al., 2022)
      Enhancer of
      Suppressor of
      NOT Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Syx17JF01937
      (Szabó et al., 2023)
      Syx17RNAi
      (Del Signore et al., 2017)
      Syx17[JF01937]
      (Nagy et al., 2015)
      Name Synonyms
      Secondary FlyBase IDs
        References (23)