Amino acid replacement: S153A.
Amino acid replacement: S151A.
Amino acid replacement: S149A.
Expression of perS149-151-153A.tG in a per01 background results in a rescue of locomotor rhythmicity compared to per01 flies, but results in activity periods which are ~2 hours longer than per01 flies resued with a wild-type per genomic fragment.
per01, perS149-151-153A.tG has abnormal locomotor rhythm phenotype, enhanceable by CkIIαTik/CkIIalpha[+]
The longer periods of circadian locomotor activity seen in per01; perS149-151-153A.tG flies are lengthened further when these flies are CkIIαTik/+.