Amino acid replacement: M538K.
T21483986A
M538K | Sara-PA
M538K
Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.
Homozygous mushroom body gamma neuron clones show normal axon pruning.
Homozygotes show deltas at the tips of the wing veins and branching of the posterior crossvein.
Homozygous third larval instar wing discs show an increase in the level of apoptosis compared to wild type.
36.4% of Sara1 embryos lacking both maternal and zygotic Sara+ function die as embryos with cellularization defects, 55.7% die as embryos without a gross morphological phenotype, while 7.8% survive to form mobile first instar larvae.
Targeting of endosomes to the central spindle is normal in Sara1 zygotic mutants.
Selected as: a suppressor of the lethality caused by expression of SaraEY07208 under the control of Scer\GAL4da.G32.
Induced on: a chromosome carrying the P{EPgy2}SdcEY07208 insertion.