FB2024_03 , released June 25, 2024
Allele: Dmel\IKKεUAS.cOa
Open Close
General Information
Symbol
Dmel\IKKεUAS.cOa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Oshima
FlyBase ID
FBal0194830
Feature type
allele
Associated gene
Dmel\IKKε
Associated Insertion(s)
Carried in Construct
P{UAS-IKKε.O}
Key Links
Transgenic product class
cDNA
(Oshima, 2006)
wild_type
(Oshima, 2006)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Oshima, 2006)
wild_type
(Oshima, 2006)
Mutagen
in vitro construct
(Oshima, 2006)
Progenitor genotype
Carried in construct
P{UAS-IKKε.O}
Cytology
Description

UAS regulatory sequences drive expression of IKKε. The IKKε open reading frame corresponds to SD10041.

(Oshima, 2006)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
IKKε
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of ik2Scer\UAS.cOa under the control of Scer\GAL4slbo.2.6 causes border cells to stall at the anterior end of the egg chamber. The stalled cells have a normal appearance and do not appear to be undergoing apoptosis.

      (Oshima, 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Carried in a plasmid and transfected into S2 cells to study the effect of the expressed product on cell shape and F actin dynamics.

      (Oshima et al., 2006)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      IKKεScer\UAS.cOa
      IKKεUAS.cOa
      ik2Scer\UAS.cOa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Oshima
      Secondary FlyBase IDs
        References (2)