FB2024_03 , released June 25, 2024
Allele: Bmul\αBgtxUAS.cYa
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General Information
Symbol
Bmul\αBgtxUAS.cYa
Species
B. multicinctus
Name
Saccharomyces cerevisiae UAS construct of Yang
FlyBase ID
FBal0187989
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

Expression of Bmul\αBgtx is under the control of UASt sequences. (Note - the coding sequence in this construct is a synthetic sequence encoding a peptide with the sequence of Bmul\αBgtx protein.)

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Bmul\αBgtxScer\UAS.cYa; Scer\GAL4GMR.PF late third-instar have disrupted the photoreceptor axon projection patterns reminiscent of semi-permissive temperature phenotypes observed in Chats2 mosaic animals. Axon fascicles form abnormal associations, resulting in unusually large and uneven bundles, instead of the normal continuous R1-R6 growth cone plexus layer. Similar phenotypes are seen when Scer\GAL4HLHmδ is used as a driver. In the latter case while axons entering the lamina terminate there, the lamina itself is somewhat disorganised. For example, glia are not confined to their proper layers, and can be found extending through the growth cone plexus.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Bmul\αBgtxScer\UAS.cYa
Bmul\αBgtxUAS.cYa
Name Synonyms
Saccharomyces cerevisiae UAS construct of Yang
Secondary FlyBase IDs
    References (1)