nerve terminal & synaptic vesicle, with Scer\GAL4hs.PS
photoreceptor cell & synaptic vesicle, with Scer\GAL4hs.PS
Overexpression of Rab5Q88L.Scer\UAS under the control of Scer\GAL4bbg-C96 results in ectopic bristles developing on the adult wing.
Flies in which the expression of Rab5Q88L.Scer\UAS, is driven by Scer\GAL4hs.PS exhibit enlarged and tubular synaptic vesicles, similar to Rab5N142I.Scer\UAS mutant flies. In contrast to Rab5N142I.Scer\UAS, Rab5Q88L.Scer\UAS facilitates the formation of multivesicular bodies (MVBs) in the photoreceptor cell body. This suggests that the function of Rab5 on synaptic vesicles is distinct from that on conventional endocytic vesicles.