FB2024_03 , released June 25, 2024
Allele: Dmel\Fas2Δ3.UAS
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General Information
Symbol
Dmel\Fas2Δ3.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0160475
Feature type
allele
Associated gene
Dmel\Fas2
Associated Insertion(s)
Carried in Construct
P{UAS-Fas2.Δ3}
Also Known As
UAS-Fas2Δ3
Key Links
Transgenic product class
dominant_negative_variant
(Szafranski and Goode, 2004)
inframe_deletion
(Szafranski and Goode, 2004)
Mutagen
Nature of the Allele
Transgenic product class
dominant_negative_variant
(Szafranski and Goode, 2004)
inframe_deletion
(Szafranski and Goode, 2004)
Mutagen
in vitro construct
(Szafranski and Goode, 2004)
Progenitor genotype
Carried in construct
P{UAS-Fas2.Δ3}
Cytology
Description

Expression of Fas2 lacking the last 3 amino acids (claimed as 'dominant-negative') is under the control of UAS sequences.

(Szafranski and Goode, 2004)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Fas2
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      In Fas2Δ3.Scer\UAS; Scer\GAL4BA3 flies the timing of delamination of the border follicle cells is normal, but their migration rate is slightly increased.

      (Szafranski and Goode, 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      K. Zito and C. S. Goodman

      (Szafranski and Goode, 2004)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Fas229C
      (Szafranski and Goode, 2004)
      Fas2Δ3.Scer\UAS
      Fas2Δ3.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (2)