Amino acid replacement: T619S. Nucleotide substitution: A2407T.
A11971538T
A2407T
T619S | cac-PA; T619S | cac-PB; T619S | cac-PC; T619S | cac-PD; T619S | cac-PE; T619S | cac-PF; T619S | cac-PG; T619S | cac-PH; T619S | cac-PI; T619S | cac-PJ; T619S | cac-PL; T619S | cac-PM; T725S | cac-PN; T619S | cac-PO; T619S | cac-PP; T619S | cac-PS; T619S | cac-PT; T619S | cac-PU
T619S
cacE(TS2)1 flies (reared at 20oC) paralyse rapidly at 36oC, with a time for 50% paralysis of 0.15 +/- 0.01 minutes. cacTS2/cacE(TS2)1 females (reared at 20oC) paralyse at 36oC, with a time for 50% paralysis of 0.31 +/- 0.03 minutes. Intracellular recordings from the dorsal longitudinal flight muscle show high-frequency bursts of activity at 36oC.
Selected as: a modifier of the cacTS2 paralytic phenotype.