Amino acid replacement: I1187T. Nucleotide substitution: T4112C. This mutation alters pre-mRNA editing.
T11954271C
T4112C
I1184T | cac-PA; I1184T | cac-PB; I1184T | cac-PC; I1184T | cac-PD; I1187T | cac-PE; I1187T | cac-PF; I1185T | cac-PG; I1185T | cac-PH; I1186T | cac-PI; I1186T | cac-PJ; I1186T | cac-PL; I1186T | cac-PM; I1290T | cac-PN; I1187T | cac-PO; I1186T | cac-PP; I1184T | cac-PS; I1184T | cac-PT; I1184T | cac-PU
I1187T
paralytic | heat sensitive (with cacTS2)
At 38oC, cacsu(TS2)1 flies (reared at 20oC) show a time for 50% paralysis of 20.43 +/- 1.88 minutes. At 38oC, cacTS2/cacsu(TS2)1 flies (reared at 20oC) show a time for 50% paralysis of 0.43 +/- 0.06 minutes.