Expression of a mutated Sara deficient in PP1c binding activity (carries the amino acid replacement F678A), tagged with Tag:MYC and Tag:polyHis at the N-terminus, is under the control of UAS sequences.
The wings of SaraF678A.Scer\UAS.T:Hsap\MYC,T:Zzzz\His6; Scer\GAL4vg.int2.1 flies show loss (notching) of both anterior and posterior wing margin and supression of wing vein L5 formation Transformation of triple row to double row bristles is seen in intact anterior wing margin.