FB2024_03 , released June 25, 2024
Allele: Ecol\lacZAct57B.-593+2
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General Information
Symbol
Ecol\lacZAct57B.-593+2
Species
E. coli
Name
FlyBase ID
FBal0131226
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
Carried in Construct
P{Act57B-lacZ.-593+2}
Also Known As
Act57B-lacZ
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Kelly et al., 2002)
Progenitor genotype
Carried in construct
P{Act57B-lacZ.-593+2}
Cytology
Description

Nucleotides -593 to +2 of the Act57B promoter, drive expression of a lacZ reporter.

(Kelly et al., 2002)
Allele components
Component
Use(s)
Regulatory region(s)
Act57B_-539/+2
Encoded product / tool
lacZ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage 11
      visceral mesoderm | intense
      (Kelly et al., 2002)
      embryonic stage 16
      embryonic/larval somatic muscle cell | intense
      (Kelly et al., 2002)
      embryonic/larval heart
      (Kelly et al., 2002)
      adult stage
      adult heart
      (Shah et al., 2011)
      Additional Information
      Statement
      Reference

      In the adult heart musculature, expression is robust in the longitudinal fibers. Expression is also seen in the cardiac tube and in the ostia showing that expression is observed in all the major cell types in the adult heart.

      (Shah et al., 2011)
       
      Marker for
      Reflects expression of
      Act57B
      (Kelly et al., 2002)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Ecol\lacZAct57B.-593+2
      Name Synonyms
      Secondary FlyBase IDs
        References (6)