FB2024_03 , released June 25, 2024
Allele: Dmel\NMcd2
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General Information
Symbol
Dmel\NMcd2
Species
D. melanogaster
Name
Microchaetae defective 2
FlyBase ID
FBal0130889
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Nature of the Allele
Progenitor genotype
Cytology
Description

G17007A nucleotide substitution in a GT donor splice site which results in a frameshift after amino acid residue D2589, producing a truncated protein containing 2589 N residues followed by an additional 10 amino acid residues.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Nucleotide change:

G3170560A

Comment:

Position of mutation on reference sequence inferred by FlyBase curator based on author statement. Mutation is in a GT donor splice site and results in a frameshift after amino acid residue D2589, producing a truncated protein containing 2589 N residues followed by an additional 10 amino acid residues.

Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In

adult thorax & microchaeta

Detailed Description
Statement
Reference

Heterozygotes show loss of thoracic microchaetae. Homozygous adult NMcd2 escapers lack 61% of thoracic microchaetae. The remaining microchaetae are evenly spaced.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
NMcd2
Name Synonyms
Microchaetae defective 2
Secondary FlyBase IDs
    References (1)