Misexpression of fra::unc-5unc-5.CD.Scer\UAS, under the control of Scer\GAL4elav.PLu, leads to defects in the normal ventral projection of the ISNb.
When expression is driven by Scer\GAL4elav.PLu a commissureless phenotype results, as for unc-5Scer\UAS.T:Ivir\HA1,T:wg.