FB2024_03 , released June 25, 2024
Allele: Dmel\neurUAS.L.Tag:MYC
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General Information
Symbol
Dmel\neurUAS.L.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0121663
Feature type
allele
Associated gene
Dmel\neur
Associated Insertion(s)
Carried in Construct
P{UAS-neur.L.Myc}
Key Links
Transgenic product class
inframe_deletion
(Lai and Rubin, 2001)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Lai and Rubin, 2001)
Mutagen
in vitro construct
(Lai and Rubin, 2001)
Progenitor genotype
Carried in construct
P{UAS-neur.L.Myc}
Cytology
Description

UASt sequences drive expression of a fragment containing amino acids 2-754 of neur, tagged with 5 Tag:MYC tags and a Kozak initiation signal and methionine codon.

(Lai and Rubin, 2001)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
neur
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      When a single copy of neurScer\UAS.T:Hsap\MYC is driven by Scer\GAL4sca-537.4 mild notum and haed sensory organ loss is seen. A loss of Sensory Organ Precursors (SOPs) is also seen in wing discs. If two copies of neurScer\UAS.T:Hsap\MYC are present (and driven by either Scer\GAL4Bx-MS1096 or Scer\GAL4sca-537.4), the opposite phenotype is provoked: although many bristles remain absent many macrochaetae positions are tufted. Missing and supernumerary SOPs are also seen in wing discs.

      (Lai and Rubin, 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      neurScer\UAS.L.T:Hsap\MYC
      neurUAS.L.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (3)