1 day memory is impaired after spaced training, but not after massed training in an olfactory associative conditioning assay in flies expressing perdsRNA.PAS.Scer\UAS under the control of either Scer\GAL4G0431, Scer\GAL4per.PK, Scer\GAL4Ddc.PL or Scer\GAL4G0338.
The defect in 1 day memory after spaced training which is caused by expression of perdsRNA.PAS.Scer\UAS under the control of Scer\GAL4G0431 is still seen if the temperature sensitive Scer\GAL80ts.αTub84B allele is used to restrict Scer\GAL4 expression to the adult stage.
1 day memory after spaced training in an olfactory associative conditioning assay is not affected in flies expressing perdsRNA.PAS.Scer\UAS under the control of Scer\GAL4Feb170.
Flies expressing perdsRNA.PAS.Scer\UAS specifically in the glial cells under the control of Scer\GAL4repo.PU show normal locomotor rhythmicity under light/dark and constant darkness conditions.
Flies expressing perdsRNA.PAS.Scer\UAS under the control of Scer\GAL4tim.PE under constant darkness conditions have an increased length of circadian period compared to controls and show some arrhythmicity of locomotor activity.
Expression of perdsRNA.PAS.Scer\UAS under the control of Scer\GAL4tim.PE results in a lengthening of the average period of circadian locomotor activity by approximately 2 hours compared to controls. Expression of perdsRNA.PAS.Scer\UAS under the control of Scer\GAL4GMR.PF results in wild-type circadian behaviour.