FB2024_03 , released June 25, 2024
Allele: Dmel\ScrtetO.Tag:HA
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General Information
Symbol
Dmel\ScrtetO.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0118338
Feature type
allele
Associated gene
Dmel\Scr
Associated Insertion(s)
Carried in Construct
P{TETo-SCR(wt)}
Key Links
Transgenic product class
cDNA
(Berry and Gehring, 2000)
wild_type
(Berry and Gehring, 2000)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Berry and Gehring, 2000)
wild_type
(Berry and Gehring, 2000)
Mutagen
in vitro construct
(Berry and Gehring, 2000)
Progenitor genotype
Carried in construct
P{TETo-SCR(wt)}
Cytology
Description

tetO regulatory sequences drive expression of a Scr cDNA. The open reading frame is tagged with Tag:HA.

(Berry and Gehring, 2000)
Allele components
Component
Use(s)
Regulatory region(s)
tetO
Encoded product / tool
Scr
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of ScrTn10\tetO.T:Ivir\HA1 driven by Tn10\tetRhs.T:Hsim\VP16 causes drastic transformations and defects in the larval head, including defects in head involution. The phenotypes seen in the larval head are indistinguishable to those seen in Scrhs.PG flies. Ectopic salivary glands are also seen in embryos of this genotype.

      (Berry and Gehring, 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      ScrTn10\tetO.T:Ivir\HA1
      ScrTn10\tetR.O.T:Ivir\HA1
      ScrtetO.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)