FB2024_03 , released June 25, 2024
Allele: Dmel\GαsL215Q.ninaE
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General Information
Symbol
Dmel\GαsL215Q.ninaE
Species
D. melanogaster
Name
FlyBase ID
FBal0102987
Feature type
allele
Associated gene
Dmel\Gαs
Associated Insertion(s)
Carried in Construct
P{ninaE-Gαs.Q215L}
Key Links
Transgenic product class
missense_variant
(Chyb et al., 1999)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Chyb et al., 1999)
Mutagen
in vitro construct
(Chyb et al., 1999)
Progenitor genotype
Carried in construct
P{ninaE-Gαs.Q215L}
Cytology
Description

cDNA encoding the short form of Gαs and carrying the amino acid replacement L215Q is expressed from a ninaE promoter.

(Chyb et al., 1999)
Allele components
Component
Use(s)
Regulatory region(s)
ninaE
Encoded product / tool
Gαs
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Photoreceptors from G-sα60AL215Q.ninaE flies show a phenoytpe similar to, but more pronounced than, photoreceptors treated by cAMP, IBMX or forskolin. The macroscopic light response is slowed down.

      (Chyb et al., 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      G-sα60AL215Q.ninaE
      GαsL215Q.ninaE
      Name Synonyms
      Secondary FlyBase IDs
        References (1)