FB2024_03 , released June 25, 2024
Allele: Dmel\ssD114.9
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General Information
Symbol
Dmel\ssD114.9
Species
D. melanogaster
Name
FlyBase ID
FBal0090118
Feature type
allele
Associated gene
Dmel\ss
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Duncan et al., 1998)
Mutagen
X ray
(Duncan et al., 1998)
Progenitor genotype
Caused by aberration
In(3R)ssD114.9
Cytology
Description

Break at 89C maps between coordinates +24 and +25 kb, within the ss transcription unit.

(Duncan et al., 1998)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      In ssD114.9/ssD115.7 mutant legs, the tarsal segments ta2, ta3, and ta4 appear to be missing while the distal-most tarsal segment is present but malformed. Small, ectopic protrusions can occasionally be observed in ta1 of these mutants. At the leg disc stage, cells that normally develop into tarsal segments ta3-ta5may possibly acquire the ta5 fate at a very early third instar stage and also incorporate the ta4 fate at subsequent stages to form a ta5/ta4 hybrid tarsus in late third instar.

      (Kozu et al., 2006)

      ssa/ssD114.9 mutants have ectopic sex combs in t2 and an ectopic joint within t1.

      (de Celis Ibeas and Bray, 2003)

      The antenna is transformed into leg in ssD114.9/Df(3R)ss-D114.4 animals.

      (Chu et al., 2002)

      ssD114.9/Df(3R)ss-D114.4 mutants exhibit cuticular defects in the arista. These include the elongation of antennal segment 2 (a2), loss of olfactory sensilla from antennal segment 3 (a3), and transformation of antennal segment 4 (a4), antennal segment 5 (a5), and arista to tarsal segments. The a2/a3 joint is still present in these animals. ssD114.9/Df(3R)ss-D114.4 mutant antennal discs, overgrowth is seen in the central area of the disc.

      (Dong et al., 2002)

      Null phenotype. Antennal transformations, reduction in bristle size and tarsal deletions.

      (Duncan et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ssD114.9
      (Natori et al., 2012, Kozu et al., 2006)
      Name Synonyms
      Secondary FlyBase IDs
        References (7)