A 3.0kb fragment of a ko cDNA is expressed, in antisense orientation, under the control of an Hsp70 promoter.
abnormal neuroanatomy
larval RP5 motor neuron
larval VL3/4 motor neuron
The VL1 muscles are not innervated by RP5 axons in 60% of cases in embryos in which koa.hs is expressed using heat shock. The RP3 axons fail to arborise into the cleft between muscles VL3 and VL4 in 72% of cases in these embryos.