FB2024_03 , released June 25, 2024
Allele: Dmel\Khc::nodUAS.lacZ
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General Information
Symbol
Dmel\Khc::nodUAS.lacZ
Species
D. melanogaster
Name
FlyBase ID
FBal0058629
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-Nod-lacZ, UAS-Nod:LacZ, Nod-β-gal, UAS-NodlacZ, UAS-NZ, UAS-Nod-β-gal
Key Links
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UASt regulatory sequences drive expression of a fusion protein that is composed of amino acids 1-320 of nod (includes the globular head motor domain), the N-terminal half of the Khc coiled-coil domain (residues 334-606) and lacZ.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference

This construct (where the Khc head domain has been replaced by the nod head domain) is a marker for minus ends of microtubules, and localizes to nuclei in developing facets.

 
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The adult eye morphology in flies expressing Khc::nodScer\UAS.T:Ecol\lacZ under the control of Scer\GAL4hs.2sev is wild-type.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Khc::nodScer\UAS.T:Ecol\lacZ
Khc::nodUAS.T:lacZ
Khc::nodUAS.lacZ
Name Synonyms
Secondary FlyBase IDs
    References (35)