FlyBase Allele Report: Dmel\Nrt::wg[Scer\FRT-.UAS.Tag:HA]

General Information

Symbol

Dmel\Nrt::wg^{Scer\FRT-.UAS.Tag:HA}

Species

D. melanogaster

Name

FlyBase ID

FBal0058487

Feature type

allele

Associated gene

Nrt::wg

Associated Insertion(s)

Carried in Construct

P{UAS(-FRT)wg::Nrt.flu}

Key Links

Transgenic product class

Mutagen

FLPase

Nature of the Allele

Transgenic product class

Mutagen

FLPase

(Zecca and Struhl, 2007, Casares and Mann, 2000, Abu-Shaar and Mann, 1998, Zecca et al., 1996)

Progenitor genotype

Nrt::wg^{FRT.UAS.Tag:HA}

(Zecca and Struhl, 2007, Casares and Mann, 2000, Abu-Shaar and Mann, 1998, Zecca et al., 1996)

Carried in construct

P{UAS(-FRT)wg::Nrt.flu}

Cytology

Description

FRT cassette has been excised, juxtaposing UAS regulatory sequences with tagged wg-Nrt coding sequences.

(Zecca et al., 1996)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Tagged with

Also carries

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

macrochaeta | ectopic, with Scer\GAL4^C-765

(Zecca et al., 1996)

wing & macrochaeta, with Scer\GAL4^C-765

(Zecca et al., 1996)

Detailed Description

Statement

Reference

Scer\GAL4^C-765 induced clones in the wing disc differentiate ectopic bristles, as does surrounding wild type tissue.

(Zecca et al., 1996)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressor of

Statement

Reference

Nrt::wg^{Scer\FRT-.UAS.Tag:HA}/Scer\GAL4^wg.PM is a suppressor of abdominal ventral acute muscle 1 founder cell phenotype of wg^l-17

(Cox et al., 2005)

Nrt::wg^{Scer\FRT-.UAS.Tag:HA}/Scer\GAL4^wg.PM is a suppressor of abdominal ventral acute muscle 2 founder cell phenotype of wg^l-17

(Cox et al., 2005)

Nrt::wg^{Scer\FRT-.UAS.Tag:HA}/Scer\GAL4^wg.PM is a suppressor of abdominal ventral acute muscle 3 founder cell phenotype of wg^l-17

(Cox et al., 2005)

Nrt::wg^{Scer\FRT-.UAS.Tag:HA}/Scer\GAL4^wg.PM is a suppressor of abdominal lateral oblique muscle 1 founder cell phenotype of wg^l-17

(Cox et al., 2005)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of Nrt::wg^{Scer\FRT-.Scer\UAS.T:Ivir\HA1} under the control of Scer\GAL4^wg.PM rescues the slou expressing founder cell phenotype in wg^l-17 embryos. In fact, there is an expansion of slou cluster II in 57% of hemisegments examined, indicating that the mesoderm is experiencing increased wg signalling.

(Cox et al., 2005)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Exists in clones, not reported as being germ-line transmitted.

(Zecca et al., 1996)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Nrt::wg^{FRT-.UAS.T:HA1}

Nrt::wg^{Scer\FRT-.Scer\UAS.T:Ivir\HA1}

Nrt::wg^{Scer\FRT-.UAS.Tag:HA}

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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