UASt regulatory sequences drive expression of the E(spl)m8-HLH coding region in which the basic domain has been neutralized.
When expressed under the influence of Scer\GAL4da.G32 or Scer\GAL4sca-537.4 can cause bristle loss of varying degrees of severity, depending on the site of insertion of P{E(spl)bd-UAST}.
Simultaneous expression of E(spl)Scer\UAS.cNa or HLHm5Scer\UAS.cNa with E(spl)1,bd-.Scer\UAS driven by Scer\GAL4da.G32 causes severe neural hypoplasia in embryos and adults, and reduces the level of neural hyperplasia in Df(3R)grob32.2.