The survival of 1 day old mutant males and females following 4 hours heat stress (38oC) is sharply decreased compared to wild-type flies. Mutant 6 day old females show decreased survival after 4 hours heat stress (38oC) compared to wild-type flies. Mutant males and females show increased survival under nutrition stress compared to wild-type flies.
Under normal conditions, 1 day old mutant females show a significantly lower juvenile hormone (JH)-hydrolysing activity compared to wild-type females. Mutant and wild-type females exposed to 38oC show a significant decrease in JH-hydrolysing activity compared to control females at 25oC. 1 day old mutant females have lower levels of stress reactivity (calculated as the percent decrease in JH-hydrolysing activity at 38oC relative to normal conditions) than control females.
Mutant flies show lower resistance to E.coli infections than wild-type flies.
A large fraction of homozygotes are arrhythmic with respect to locomotor activity when kept in constant darkness at 24oC, and the average signal-to-noise ratio is lower than wild-type. At 20oC, most homozygotes have weak rhythmicity or are arrhythmic, at 28oC, most homozygotes have significant periodicity. The circadian period tends to be shorter at 20oC and longer at 28oC. The eclosion rhythm is normal.
No sensitivity to 0.2M beta-alanine.
