FB2024_03 , released June 25, 2024
Allele: Dmel\fjp1
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General Information
Symbol
Dmel\fjp1
Species
D. melanogaster
Name
FlyBase ID
FBal0049503
Feature type
allele
Associated gene
Dmel\fj
Associated Insertion(s)
P{lacW}fjp1
Carried in Construct
Also Known As
fj-lacZ, four-jointed-LacZ
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Brodsky and Steller, 1996)
Progenitor genotype
Associated Insertion(s)
P{lacW}fjp1
Cytology
Description

Insertion of P{lacW} into the 5' untranslated region of the fj transcription unit, in the same orientation as the fj direction of transcription.

(Brodsky and Steller, 1996)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygotes have ectopic wing vein material between the L1 and L2 veins.

      (Lim et al., 2005)

      Wings from fjd1 homozygotes are shortened - specifically the region between the anterior and the posterior crossvein is significantly reduced, whilst the proximal wing regions are unaffected. Wings often contain ectopic wing vein material. Homozygous mutant animals have shorter and "dumpier" abdominal regions than wild-type. Abdomens are about 221 μm at the dorsal midline compared to about 261 μm in wild-type.

      (Zeidler et al., 2000)

      Legs are shorter than wild type with four instead of five tarsal segments. The wing is reduced in length. Eye surface is deformed, though this phenotype is only evident for stronger alleles and has variable penetrance and expressivity.

      (Brodsky and Steller, 1996)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Adding fjp1/fjd1 has little effect on the wing area of dsUAO71/ds38k flies.

      Adding fjp1/fjd1 dramatically reduces the wing area of flies expressing dsAct5C.T:Avic\GFP-EGFP in a dsUAO71/ds38k background.

      Adding fjp1/fjd1 has no effect on the wing area of flies expressing dsSAx3.Act5C.T:Avic\GFP-EGFP in a dsUAO71/ds38k background.

      Adding fjp1/fjd1 has no effect on the wing area of flies expressing dsSDx3.Act5C.T:Avic\GFP-EGFP in a dsUAO71/ds38k background.

      (Brittle et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Δ2-3-induced excision of the P{lacW} can be accompanied by reversion of the mutant phenotype.

      (Brodsky and Steller, 1996)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      References (10)