FB2024_03 , released June 25, 2024
Allele: Dmel\scrths.PR
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General Information
Symbol
Dmel\scrths.PR
Species
D. melanogaster
Name
heat shock construct of Roark
FlyBase ID
FBal0046412
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

2.2kb XbaI fragment containing the full scrt open reading frame expressed from an Hsp70 promoter.

Allele components
Component
Use(s)
Regulatory region(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Ectopic expression of scrt generates extra neurons, both embryonic and adult, depending on the timing of the heat shock. Ommatidia from heat shocked eye discs frequently have eight rather than seven photoreceptor cells. Heat induction at puparium formation causes loss of macrochaetae on the thorax and head, and heat shocks at later times cause dramatic loss of microchaetae from thorax, head, legs and wing margin. Interommatidial bristles are also missing. Heat shocks as late as 15-24 hours after pupariation cause absence of macrochaetae and microchaetae on the abdomen, missing posterior crossveins and, less frequently, missing anterior crossveins.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
scrths.PR
Name Synonyms
heat shock construct of Roark
Secondary FlyBase IDs
    References (2)