FB2024_03 , released June 25, 2024
Allele: Dmel\lphA2
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General Information
Symbol
Dmel\lphA2
Species
D. melanogaster
Name
FlyBase ID
FBal0046098
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Mutagen
    Nature of the Allele
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Homozygous larvae are negatively photokinetic with a stimulus indice significantly higher than wild type control. Heterozygotes have an indice similar to wild type, transheterozygotes with lphA1 have a higher indice and transheterozygotes with rdgA1 or oc1 have a lower indice. Transheterozygotes with Df(1)C52 have an extremely high indice and are blind. Homozygotes respond normally to light in a phototaxis assay, ERG is normal, males perform vigorous courtship in response to wild type females and perform the behaviour 'orientation', rarely performed by blind or visually impaired males. Hemizygotes are blind. Mutation does not affect larval responses to olfactory or taste stimuli.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    lphA2
    Name Synonyms
    Secondary FlyBase IDs
      References (1)