FB2024_03 , released June 25, 2024
Allele: Ecol\lacZRh3.343P
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General Information
Symbol
Ecol\lacZRh3.343P
Species
E. coli
Name
FlyBase ID
FBal0041884
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
Carried in Construct
P{Rh3.343,lacZ}
Also Known As
rh3-lacZ
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Papatsenko et al., 1997, Fortini and Rubin, 1990)
Progenitor genotype
Ecol\lacZRh3.PF
(Fortini and Rubin, 1990)
Carried in construct
P{Rh3.343,lacZ}
Cytology
Description

lacZ expression is driven by Rh3 promoter fragment from -343bp to +18bp.

(Fortini and Rubin, 1990)
Allele components
Component
Use(s)
Encoded product / tool
lacZ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      dorsal margin photoreceptor cell R7
      (Fortini and Rubin, 1990)
      dorsal margin photoreceptor cell R7 | anterior
      (Fortini and Rubin, 1991)
      dorsal margin photoreceptor cell R8
      (Fortini and Rubin, 1990)
      dorsal margin photoreceptor cell R8 | anterior
      (Fortini and Rubin, 1991)
      medulla | dorsal | restricted
      (Fortini and Rubin, 1991)
      medulla | restricted
      (Wernet et al., 2003)
      photoreceptor cell R7 | subset
      (Wernet et al., 2003, Papatsenko et al., 2001, Papatsenko et al., 1997, Fortini and Rubin, 1991, Fortini and Rubin, 1990)
      Additional Information
      Statement
      Reference

      Expression is observed in a subset of R7 cells, and in the axonal projections of those cells.

      (Wernet et al., 2003)

      Expression is observed in <i>pale</i> R7 cells, paired with R8 cells expressing Rh5. Additionally, Rh3 is expressed in both R7 and R7 cells in the dorsal margin of the retinal.

      (Papatsenko et al., 2001)

      Expression is observed in R7 cells paired with Rh5-expressing R8 cells.

      (Papatsenko et al., 1997)

      Expression is observed in around 25 paired R7 and R8 cells along the dorsal anterior margin of the eye, as well as in 30% of other R7 cells. Expression is also observed in an arc of photoreceptor synaptic terminals along the dorsal posterior rim of the medulla neuropil.

      (Fortini and Rubin, 1991)

      Expression is observed in about 30% of R7 cells, as well as in all R7 and R8 cells of the dorsal margin of the eye.

      (Fortini and Rubin, 1990)
       
      Marker for
      dorsal margin photoreceptor cell R7
      (Papatsenko et al., 2001, Fortini and Rubin, 1991, Fortini and Rubin, 1990)
      dorsal margin photoreceptor cell R8
      (Fortini and Rubin, 1991, Fortini and Rubin, 1990)
      photoreceptor cell R7 of pale ommatidium
      (Wernet et al., 2003, Papatsenko et al., 1997, Fortini and Rubin, 1991, Fortini and Rubin, 1990)
      Reflects expression of
      Rh3
      (Wernet et al., 2003, Papatsenko et al., 2001, Papatsenko et al., 1997, Fortini and Rubin, 1991, Fortini and Rubin, 1990)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Ecol\lacZRh3.343P
      lacZRh3.343P
      Name Synonyms
      Secondary FlyBase IDs
        References (6)