FB2024_03 , released June 25, 2024
Allele: Ecol\lacZems.1.2
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General Information
Symbol
Ecol\lacZems.1.2
Species
E. coli
Name
FlyBase ID
FBal0041260
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
Carried in Construct
P{ems-lacZ.1.2}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Taylor, 1998, Jones and McGinnis, 1993)
Progenitor genotype
Carried in construct
P{ems-lacZ.1.2}
Cytology
Description

A 1.2kb EcoRI fragment from -3.2 to -2.0 relative to the the ems transcription start site, plus an Hsp70 basal promoter control expression of a lacZ reporter.

(Jones and McGinnis, 1993)
Allele components
Component
Use(s)
Regulatory region(s)
ems
ems_ARFE
Encoded product / tool
lacZ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage 11 -- 17
      embryonic/larval posterior spiracle | precursor
      (Jones and McGinnis, 1993)
      embryonic epidermis of embryonic abdominal segment 8
      (Jones and McGinnis, 1993)
      embryonic stage 12 -- 17
      filzkorper
      (Jones and McGinnis, 1993)
      embryonic stage 14 -- 17
      organism | anterior
      (Jones and McGinnis, 1993)
      embryonic/larval posterior spiracle
      (Jones and McGinnis, 1993)
      Additional Information
      Statement
      Reference

      In embryo, starting at stage 11, expression in primordia of or cells of the posterior spiracles; starting in embryonic stage 14, expression observed in unidentified antereo-dorsal cells, just dorsal to the pharyngeal muscle.

      (Jones and McGinnis, 1993)
       
      Marker for
      filzkorper
      (Bachiller et al., 1994)
      Reflects expression of
      ems
      (Jones and McGinnis, 1993)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      ems enhancer-reporter construct.

      (Jones and McGinnis, 1993)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Ecol\lacZems.1.2
      lacZems.1.2
      Name Synonyms
      Secondary FlyBase IDs
        References (11)