FB2024_03 , released June 25, 2024
Allele: Dmel\ifm8.hs
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General Information
Symbol
Dmel\ifm8.hs
Species
D. melanogaster
Name
FlyBase ID
FBal0039421
Feature type
allele
Associated gene
Dmel\if
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
in vitro construct
(Bunch et al., 1998, Graner et al., 1998, Fogerty et al., 1994, Bunch and Brower, 1992)
Progenitor genotype
Cytology
Description

Construct: Encodes if lacking those amino acids encoded by exon 8, driven by a heat shock promoter.

(Fogerty et al., 1994)

if m8 cDNA is expressed under the control of an Hsp70 promoter.

(Bunch and Brower, 1992)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Schneider cells transformed with myshs.PF and ifm8.hs show spreading when the substrate has been coated with Tig gene product, though spreading is less extensive than for ifC.hs.

      (Fogerty et al., 1994)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Carried in a plasmid, transfected into S2 cells and used in cell spreading assays.

      (Bunch et al., 1998)

      Carried in a plasmid, expressed in Schneider line 2 cells and used in cell spreading assays.

      (Graner et al., 1998)

      Coexpressed in S2 cells with mys and used to study the phosphorylation of Fak56D upon cell attachment to the extracellular matrix.

      (Fujimoto et al., 1999)

      Carried in plasmid 'pHSαPS2C', transfected into S2/M3 cells, assayed for expression and used in cell spreading assays.

      (Bunch et al., 2006)

      Carried in plasmid "pHSαPS2m8" and transfected into S2 cells.

      (Subramanian et al., 2007)

      Carried in plasmid "pHSPS2(m8)", transfected into S2/M3 cells, assayed for expression and used in cell spreading assays.

      (Bunch and Brower, 1992)

      Carried in plasmid "HSPS2(m8)".

      (Fogerty et al., 1994)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ifm8.hs
      αPS2m8
      (Graner et al., 1998)
      Name Synonyms
      Secondary FlyBase IDs
        References (9)