FB2024_03 , released June 25, 2024
Allele: Dmel\Krhs.PS
Open Close
General Information
Symbol
Dmel\Krhs.PS
Species
D. melanogaster
Name
heat shock construct of Struhl
FlyBase ID
FBal0038886
Feature type
allele
Associated gene
Dmel\Kr
Associated Insertion(s)
Carried in Construct
P{hsp70-Kr}
Key Links
Transgenic product class
wild_type
(Langeland et al., 1994)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Langeland et al., 1994)
Mutagen
in vitro construct
(Hoch and Jackle, 1998, Hartmann et al., 1997, Langeland et al., 1994)
Progenitor genotype
Carried in construct
P{hsp70-Kr}
Cytology
Description

Kr expression is driven by an Hsp70 promoter.

(Langeland et al., 1994)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
Kr
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      A heat-shock induced pulse of Krhs.PS expression just before the birth of the U3 lineage results in a high proportion of hemisegments having ectopic U3 neurons. Progressively later pulses of Krhs.PS expression generate a decreasing frequency of ectopic U3 neurons.

      (Cleary and Doe, 2006)

      Embryos expressing Krhs.PS using heat shock between 4 to 6 hours after egg laying develop additional Malpighian tubule tip cells.

      (Hoch and Jackle, 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      G. Struhl.

      (Langeland et al., 1994)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Krhs.PS
      Name Synonyms
      heat shock construct of Struhl
      (Langeland et al., 1994)
      Secondary FlyBase IDs
        References (8)